A room temperature route for doping silica particles with Cu nanoparticles to achieve hybrid structures is introduced. First, silica nanoparticles were synthesized according to the well-known Stöber method by hydrolysis and condensation of TEOS in a mixture of ethanol with water, using ammonia as catalyst to initiate the reaction. These SiO2 nanoaprticles were dried at 100 oC. We measured the size of these nanoparticles with transmission electron microscopy (TEM). Second, Cu-SiO2 nanoparticles were synthesized by reaction with CuCl2 and SiO2 nanoparticles in presence of catalyst at room temperature for 12 hrs. Results show silica nanoparticles of about 70 nm size with regularly deposited Cu nanoparticles. Cu-SiO2 nanoparticles were investigated with TEM images, energy dispersive X-ray analysis (EDX) spectrum and so on.