The polycrystalline compounds of the general formula Cd1-xNixCr2Se4 have been prepared by the ceramic method in closed silica tubes using CdSe, NiSe and Cr2Se3. The phase composition and structural data have been determined by X-ray diffraction. The observed symmetry is cubic, space group Fd 3m . Apart from spinel phases, other phases were observed: CdSe, NiSe2 and Cr5.6Se8. Depending on amount of nickel, nickel ions can occupy tetrahedral and octahedral sites.