Paper Title:
Biocompatible and Biodegradable Triblock Copolymers via ATRP
  Abstract

Novel well-defined ABA-type triblock copolymers, (PMAIPGal-b-PLA-b-PMAIPGal), were synthesized by a three-step procedure: (a) melt polycondensation of L-lactic acid using stannous chloride (SnCl2•2H2O) as a catalyst, resulting in a hydroxyl-terminated prepolymer by alkyd condensation with 1,4-butanediol, followed by (b) esterification of the PLA hydroxyl end-groups with 2-bromoisobutyryl bromide, and (c) ATRP of 6-O-methacryloyl-1,2;3,4-di-O-isopropylidene-D-galactopyranose (MAIPGal) by the bromoisobutyryl initiating groups. The resultant copolymers were characterized by 1H NMR spectroscopy and gel permeation chromatography (GPC). The biocompatible and biodegradable copolymers have potential applications as tissue engineering biomaterials or controlled release drug delivery systems.

  Info
Periodical
Solid State Phenomena (Volumes 181-182)
Chapter
V. Related Materials
Edited by
Yuan Ming Huang
Pages
356-359
DOI
10.4028/www.scientific.net/SSP.181-182.356
Citation
X. D. Tang, X. Wang, Y. Y. Dou, M. S. Pei, "Biocompatible and Biodegradable Triblock Copolymers via ATRP", Solid State Phenomena, Vols. 181-182, pp. 356-359, 2012
Online since
November 2011
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Price
$32.00
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