Papers by Author: Baoe Li

Abstract: In this paper, antibacterial silver-containing hydroxyapatite coating was prepared by vacuum plasma spraying method and osteoblasts were seeded onto the surface of the coating to evaluate its cytocompatibility. The results indicated that the cells proliferated well on the samples, and the proliferation rate on the silver-containing hydroxyapatite coating was a little bit higher than that on the silver-free hydroxyapatite coating. The contact angle of water drop on the coating was measured, and it was found that the contact angles of the silver-containing hydroxyapatite coatings were smaller than the hydroxyapatite coating. The improvement of hydrophilicity for the silver-containing hydroxyapatite coating could be beneficial to the cells proliferation on its surface. It can be concluded that the addition of silver in the hydroxyapatite coating endowed the coating with antibacterial property while maintaining its excellent cytocompatibility.

Abstract: In this work, nano-TiO2 powders were deposited onto Ti-6Al-4V substrates to produce coating using plasma spraying. The TiO2 coatings were respectively by acid, alkali and heat treatment to produce the bioactive surface. The bioactivity of TiO2 coating was examined by simulated body fluids test. The results obtained indicated apatite was formed on the surfaces of nano-TiO2 coatings treated by H2SO4, HCl and HF solutions, while it could not be formed on the surface of the nano-TiO2 coating treated by NaOH solution at low concentration. After alkali attack and heat treatment at 600°C, the bioactivity of nano-TiO2 coating disappeared.

Abstract: In this work, collagen type I was covalently grafted on the surface of plasma sprayed titania coatings to improve their biocompatibility. The plasma sprayed titania coatings were pretreated by sodium hydroxide to induce the formation of hydroxyl groups which can covalently graft collagen, rendering the collagen having good stability. The dependence of collagen grafting on the sodium hydroxide treatment conditions (concentration, time and temperature) was investigated by measuring the amount of collagen grafted on the titania surface. The biocompatibility of the titania coatings with grafted collagen was evaluated by in vitro cell culture. The results showed that the amount of collagen grafted on the titania coatings increased with the concentration of the sodium hydroxide and the treating temperature, while that on the coating is slightly dependent on the treatment time in sodium hydroxide. In vitro cell culture test proved the positive effects of collagen on the biocompatibility of the plasma sprayed titania coating.