Papers by Author: D. Raković

Abstract: The complex behavior of microparticles in a solution calls for different theoretical backgrounds. Here, we follow the line of two, recently developed theories on individuality, on the one hand, and conformational transitions of macromolecules in a solution, on the other. Given as separate theories, the two models may raise certain controversy in respect to their mutual consistency. Needless to say, their mutual consistency is necessary for the validity of the theories both in a general context as well as in search for a unified physico/chemical picture concerning the microparticles in a solution dynamics. We point out the consistency of these theories based on the definition of a molecule through its constituent subsystems (e.g. the center-of-mass and the “conformation” subsystems).

Abstract: Our recently proposed quantum approach to biomolecular isomeric-conformational changes and recognition processes, additionally supported by biomolecular resonant recognition model and by quantum-chemical theory of biomolecular non-radiative resonant transitions, is hereby extended to cascade resonant transitions via close intermediate participating isomeric states - which might be related to polaron/soliton-like energy and charge transport mechanisms in Q1Dmolecular chains, whose relevance is explored in this paper.

Abstract: Our recently proposed quantum approach to biomolecular recognition processes is hereby additionally supported by biomolecular Resonant Recognition Model and by quantum-chemical theory of biomolecular non-radiative resonant transitions. Previously developed general quantumdecoherence framework for biopolymer conformational changes in very selective ligandproteins/ target-receptors key/lock biomolecular recognition processes (with electron-conformational coupling, giving rise to dynamical modification of many-electron energy-state hypersurface of the cellular quantum-ensemble ligand-proteins/target-receptors biomolecular macroscopic quantum system, with revealed possibility to consider cellular biomolecular recognition as a Hopfield-like quantum-holographic associative neural network) is further extended from nonlocal macroscopicquantum level of biological cell to nonlocal macroscopic-quantum level of biological organism, based on long-range coherent microwave excitations (as supported by macroscopic quantum-like microwave resonance therapy of the acupuncture system) - which might be of fundamental importance in understanding of underlying macroscopic quantum (quantum-holographic Hopfieldlike) control mechanisms of embryogenesis/ontogenesis and morphogenesis, and their backward influence on the expression of genes.

Abstract: In this paper we describe the biopolymer chain folding problem in the framework of the so-called quantum decoherence theory. As we propose a rather qualitative scenario yet bearing generality, it seems this provides promising basis for the solution-in-principle of the (semi) classically hard kinetic problem of biopolymer chain folding from coiled to native conformation in highly selective ligand proteins/target-receptors biomolecular recognition processes, implying underlying macroscopic quantum nonlocality on the level of biological cell.

Abstract: Contemporary trends in science and technology are characterized by integration of biological and technical systems, like in nanotechnology, nanobiology, and quantum medicine. In our case, we were motivated by a necessity to understand charge transport through microtubular cytoskeleton as a constitutive part of acupuncture system. The high frequency component of acupuncture currents, widely exploited in microwave resonance stimulation of acupuncture system in the past decade, implies that explanation of the cytoplasmatic conductivity should be sought in the framework of Frohlich theory. Accordingly, in this paper we critically analyze the problem of the microwave coherent longitudinal electrical oscillations as a theoretical basis for understanding soliton phenomena in microtubules, showing that charged kink-soliton nonlinear microtubular excitations might be a good candidate for charge transport in microtubules.