Papers by Author: Johannes Sitterberg

Abstract: The preparation and charactersiation of novel lipid coated PLGA nanoparticles was investigated in the presented study. The size of the pure nanoparticles could be adjusted in dependence on the stabilizer content. The supported lipid bilayer surrounding the nanoparticles was formed by the liposome spreading technique. The Lipid- coated nanoparticles were characterised using Photon Correlation Spectroscopy (PCS) and atomic force microscopy (AFM) investigations. The bioadhesive properties was proofed in a cell culture model.

Abstract: We report the surface modification of a cellulose dialysis membrane by tetraether lipids and silver colloids to improve the antiadhesive and antibacterial properties of the biopolymer. The lipid was covalently attached to the membrane via the bivalent linker cyanuric chloride. The biologically evaluation show that the adhesion of serum components as well as bacteria, was decreased by this novel coating.