Papers by Author: Lei Ni

Abstract: In order to test the performance of the resulting membrane oxygenator, a model was constructed to simulate the inner and extracorporeal gas exchange of the human body. The oxygenation capacity of the membrane oxygenator was studied using fresh bovine blood with added anticoagulants as the test medium. The oxygenation performance of the prepared membrane was equal to that of the commercial membrane. After six hours of operation, the oxygen saturation (SaO2) was above 95%, and the partial pressure of oxygen (PaO2) was over 13.5 kPa (100 mmHg). This model was constructed in accordance with the basic principles of extracorporeal circulation, and could be used to investigate the oxygenation performance of a membrane oxygenator, as well as to study the basic principles of extracorporeal circulation.

Abstract: Polypropylene/polysulfone composite ultrafiltration membrane was prepared though coating method using microporous polypropylene hollow fiber membrane as a support layer and polysulfone membrane as a functional layer. Membranes of different pore sizes were prepared by L-S phase translation though changing the concentration of PS. The properties of the composite membrane include water flux and rejections of PEG-2000 were studies. The flux of 78 L/m²h and 98 % rejection was achieved at PS concentration of 11%, Polyvinylpyrrolidone of 4 %, liquid phase coagulation time of 3 hours.

Abstract: Artificial lung also called as oxygenator which performs a function of exchanging O2 and removing CO2 from blood. Due to its good performance at the exchange area, oxygenation, etc, hollow fiber membranes have become the main research direction of artificial lung. Polypropylene (pp) hollow fiber membranes made by the melt-spinning and cold-stretching methods (MSCS) in this study. Through the research on the membrane manufacture process and technology optimization to prepare suitable membrane for artificially lung. The performance of membrane was affected by the melt-draw ratio and spinning temperature, annealing temperature, and the proportional relations of cold stretch with hot stretch. The results of the study show that improve melt-draw ratio, select the appropriate annealing conditions and the reasonable ratio of hot stretch with cold stretch can effectively increase the air flux of pp hollow fiber membrane.