Papers by Author: S.G. Kim

Abstract: This study analyzed the examination records and radiographs of 247 patients (144 male, 103 female) who received an OSSTEM Implant (Seoul, Republic of Korea) at the dental clinic at Chosun University, Korea, between January 2002 and December 2005. The overall success rate in patients who received an OSSTEM Implant from surgeons of the Department of Oral Surgery at our hospital was 93.1%, making the overall failure rate relatively low (6.9%). The failure rate for the maxillary molar tooth was slightly higher, at 9.95%, probably as a result of its relatively lower bone quality and reduced osteoid volume caused by pneumatization of the maxillary sinus. Thus, to determine appropriate treatment, it is necessary to accurately determine bone quality and volume. This can be achieved with implant placement analysis of computed tomography, precise preoperative planning, and sufficient technical experience.

Abstract: We evaluated the bone healing effect of grafting with synthetic β-tricalcium phosphate (β-TCP; Cerasorb®), bovine-derived hydroxyapatite (HA; Bio-Oss®), and a mixture of β-TCP and HA in rats. Each material was grafted in prepared 8-mm frontal bone defects in 15 rats. The control group underwent surgery without any grafting materials and was examined after 4 weeks, whereas the experimental groups received grafting materials and were examined after 1, 2, and 4 weeks. After implantation, the rats were sacrificed for histomorphometric studies using light microscopy, and the data were analyzed using analysis of variance. Considerable inflammation and fibrosis were observed after 1 and 2 weeks in all experimental groups, whereas the inflammation was reduced and fibrosis was stabilized after 4 weeks. New bone formation was observed at the defect margin. Statistically, there was no difference in new bone formation among the three experimental groups. In conclusion, there was no difference in new bone formation using Bio-Oss®, Cerasorb®, and a mixture of Bio-Oss® and Cerasorb®.

Abstract: We compared the effect of osteotomies performed using piezoelectric surgery (Piezosurgery®) and the conventional bur method on new bone formation in the rabbit mandible, focusing on light-microscopy observations of the early healing process after 1, 2, and 4 weeks. The time required to perform the osteotomy was also compared. We showed that piezoelectric surgery and the conventional bur method had no marked difference on early bone healing, although the osteotomy time was shorter with the conventional bur method than with Piezosurgery. Because the instrument used in Piezosurgery is sharp and more controllable, piezoelectric surgery should be more useful for delicate surgery, such as maxillary sinus lifting and segmental osteotomies, with the fewest complications.

Abstract: I tested the effectiveness of a particulate dentin and plaster of Paris mixture as a bone substitute. Histologic analysis indicated that all of the bone defects surrounding the implants treated with particulate dentin/plaster of Paris were filled with new bone 6 and 12 weeks after surgery. No significant differences were observed in the new bone forming activity in any species (human, bovine, pig, rabbit, and dog). No cytotoxicity was detected in cell cultures with added particulate dentin extract and no specific allergic reactions were seen in the hypersensitivity test. These results suggested that the combination of particulate dentin and plaster is suitable as an alternative bone substitute.

Abstract: This study evaluated the efficacy of periodontal tissue regeneration using guided tissue regeneration (GTR) with a mixture of tooth ash and plaster as a bone substitute material in the treatment of class II furcation defects in dogs. GTR was performed at the site of a surgically formed mandibular premolar bifurcation area in dogs. Four adult dogs were used in the animal study. The animals were in a good periodontal state without any systemic disease. A resorbable membrane (Bio-Gide®, Swiss) and bone graft material using a mixture of tooth ash and plaster were used to examine the biological activity. The defect in the control group was filled a Bio-Gide® only. For the experimental group, the defects were filled with a mixture of tooth ash and plaster and covered by a Bio-Gide®. Oral rinsing with 0.12% chlorhexidine was performed twice a day for 2 weeks. In control group, new bone formation was observed adjacent to the preexisting bone. Soft tissue ingrowth was also noted. In experimental group, new lamellar type trabecular bone formation as well as centum and PDL regeneration was observed in the base of the infrabony pocket. More bone regeneration would be expected when GTR is performed using a mixture of human tooth-ash and plaster of Paris as a bone graft material.

Abstract: This studied determined the clinical effect of antibiotic use at the site of bone defect restoration in patients with osteoporosis, using tooth ash and plaster of Paris in ovariectomized rats. Forty-eight rats were assigned to four groups randomly and each group was further divided into 4 and 8 weeks after implantation. Histologic sections of the defects were obtained after surgery for histomorphometric analysis. Comparing each week, a significant difference was seen in bone formation by 4 weeks. Compared to controls, new bone formation increased significantly with tooth ash and saline, tooth ash and gentamicin, and tooth ash and gentamicin after ovariectomy. Tooth ash and saline resulted in the best bone formation. The degree of new bone formation was slightly lower when tooth ash and gentamicin were used compared to when tooth ash and saline were used. When tooth ash and gentamicin were compared according to ovariectomy, bone formation was significantly inhibited by ovariectomy at 4 weeks, while no significant difference was seen at 8 weeks.

Abstract: This study examined the role of tissue adhesives during early healing and the effects of tooth ash and plaster of Paris on bone healing in the presence of osteoporosis. Sixty rats were assigned to five groups randomly and each group was further divided into two subgroups, which were examined 4 and 8 weeks after implantation. Histologic sections and histomorphometric analysis of defects were obtained 4 and 8 weeks after surgery. Bone formation was significantly better in the non-ovariectomized groups compared to the ovariectomized group. A mixture of tooth ash and plaster of Paris is recommended, but not tissue adhesives, in ovariectomized cases.