Papers by Author: Zhen Sheng Li

Abstract: In order to prepare the bone repair scaffold materials that could employ the sources of the injured bone, the bioactive HA and BMP-2 were added into the biomaterial PLLA. The four scaffold materials, PLLA, PLLA/HA, PLLA/BMP-2 and PLLA/HA/BMP-2 were prepared by electrospinning. The SEM results revealed that the morphology of the 7wt% PLLA fibers was better than the 5wt% PLLA fibers, and the HA nanoparticles were distributed uniformly in fibers. The calculated surface energy of the PLLA/HA/BMP-2 scaffold was higher compared with other three scaffolds, this result fit well with the result of MTT assay of the four scaffold materials, and the MTT assay showed that the MG63 cells on the PLLA/HA/BMP-2 scaffold material proliferated faster compared with the PLLA/HA or PLLA/BMP-2. It is logical to assume that PLLA/HA/BMP-2 scaffold material is a promising material for bony tissue repair.

Abstract: Nano-titania ceramics is a potential biomaterial for orthopaedic application. In our previous studies, a bioactive nano-titania ceramics was prepared by using alkali-heat treatment. In this paper, hydroxyapatite was used as a grain growth inhibitor additive to get nano-titania ceramics with different grain size, and the effect of grain size on the bioactivity was studied in vitro.

Abstract: After the Tantalum metal was subjected to the anodic oxidation at suitable voltage in 2M H2SO4 solution, tantalum oxide with rhombic or amorphous structure formed on the metal surface. The Oxide showed apatite formation ability in simulative body fluid at 6d. It meant the anodic oxidation treatment ia an effective method to accelerate the bioactivity of tantalum metal.