Metallosis - Literature Review and Particular Cases Presentation

Abstract:

Metallosis is an adverse event developed in relation with an orthopedic implant. It was brought into attention by metal on metal total hip arthroplasty. Lately, cases were diagnosed in total knee, total elbow, and spinal surgery. Metallic debris - released because of wear or corrosion - start an inflammatory response in a chronic condition. Beside local effects, systemic effects are also described; among them toxic effects, neurological and psychiatric, alteration in thyroid and heart function, skin rushes and discoloration. Diagnosis is helped by x-ray examination but is based on fluid aspiration with ions level determination and histological examination. Osteolysis phenomena induced by metallosis may compromise bone ingrowth and promote implant loosening; as result bone stock may be compromised. The cases we present have a particular development pattern; each of them was initiated as a result of atypical behavior of the implants. Two of them necessitated bone grafting in order to replace the reduced bone stock and all three required revision surgery. The cases emphasize the diagnosis methodology and the possible complications encountered during orthopedic implant surgery.

• Periodical: Key Engineering Materials (Volume 745)
• Pages: 77-90
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.745.77
• Online since: July 2017
• Authors: Rodica Marinescu*, Claudiu Socoliuc, Iozefina Botezatu, Dan Laptoiu, Dan Voinescu
• Keywords: Clinical, Diagnosis, Metallic Biomaterials, Metallosis, Orthopedic Implant

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