Papers by Keyword: Allylamine

Abstract: Coronary stents are metallic (316L stainless steel) devices employed during balloon angioplasty to reopen and prevent the re-obstruction of a diseased narrowed area within a coronary artery. To reduce restenosis rate, bare metal stent coating is a promising solution. The coating can act as an anticorrosive barrier against the aggressive properties of biological environment, improving the long-term safety of the device. The goal of this study is to develop a dry process to isolate metallic surface from the biological environment by depositing a thin plasma polymerized allylamine (CH2=CH-CH2-NH2) film on the metallic surface. Plasma polymerized allylamine films were deposited on flat electropolished 316L stainless steel samples in a low pressure plasma reactor (70 kHz). Chemical composition of the coatings has been analysed as a function of the discharge power and treatment time. Moreover, special attention has been paid on the stability of the coating after immersion during 24 hours in D.I. water. Finally, to mimic stent expansion conditions, a “small punch test” has been used to investigate the adhesive properties of the coating. Our results demonstrate that is possible to deposit a stable, cohesive and adhesive plasma polymerized allylamine thin film which can be used as a coating for cardiovascular stents

Abstract: In the present work, technique of plasma polymerization was used to generate amido (- NH2) and carboxyl (-COOH) on titanium surface for immobilizing bovine serum albumin (BSA). After plasma polymerization of allylamine and crylic acid, the contact angle with respect to double distilled water significantly increased. Surface components were detected by X-ray photoelectron spectroscopy and Fourier transform infrared reflection-absorption spectroscopy. The results showed that BSA was successfully immobilized on the titanium surface and the amounts of BSA on specimens were relied on the properties of thin film deposited through plasma polymerization, which was corresponding to the ultraviolet spectrophotometer result.