Papers by Keyword: Artificial Lung

Abstract: In order to test the performance of the resulting membrane oxygenator, a model was constructed to simulate the inner and extracorporeal gas exchange of the human body. The oxygenation capacity of the membrane oxygenator was studied using fresh bovine blood with added anticoagulants as the test medium. The oxygenation performance of the prepared membrane was equal to that of the commercial membrane. After six hours of operation, the oxygen saturation (SaO2) was above 95%, and the partial pressure of oxygen (PaO2) was over 13.5 kPa (100 mmHg). This model was constructed in accordance with the basic principles of extracorporeal circulation, and could be used to investigate the oxygenation performance of a membrane oxygenator, as well as to study the basic principles of extracorporeal circulation.

Abstract: Artificial lung also called as oxygenator which performs a function of exchanging O2 and removing CO2 from blood. Due to its good performance at the exchange area, oxygenation, etc, hollow fiber membranes have become the main research direction of artificial lung. Polypropylene (pp) hollow fiber membranes made by the melt-spinning and cold-stretching methods (MSCS) in this study. Through the research on the membrane manufacture process and technology optimization to prepare suitable membrane for artificially lung. The performance of membrane was affected by the melt-draw ratio and spinning temperature, annealing temperature, and the proportional relations of cold stretch with hot stretch. The results of the study show that improve melt-draw ratio, select the appropriate annealing conditions and the reasonable ratio of hot stretch with cold stretch can effectively increase the air flux of pp hollow fiber membrane.

Abstract: The purpose of this study was to investigate the effect of vibration device in gas transfer rate for usage as intravenous lung assist device. Specific attention was focused on the effect of membrane vibration. Quantitative experimental measurements were performed to evaluate the performance of the device, and to identify membrane vibration dependence on hemolysis. Scaling analysis was then used to infer the dimensionless groups that correlate the performance of a vibrated hollow tube membrane oxygenator. The experimental design and procedure are then given for a device for assessing the effectiveness of membrane vibrations. This ILAD is used to provide some insight into how wall vibrations might enhance the performance of an intravascular lung assist device. The time and the frequency response of PVDF sensor were investigated through various frequencies in the ILAD. In these devices, the flow of blood and the source of oxygen were separated by a semipermeable membrane allows oxygen to diffuse into and out of the f1uid, respectively. The results of experiments have shown vibrating ILAD performs effectively.