Papers by Keyword: Blood Cells

Abstract: The formation of biofilm (Biofouling) in different surface is the great concern in types of fields, especially in medical and health system as well as in membrane technology. The present study deals with the synthesis and characterization of Al₂O₃ nanopowders with antibacterial activity which can be a potentially utilized material for biocompatible implants. Nanostructure was synthesized based on sol-gel method and then, crystallite size, and microstructural and morphological characterization of nanostructure were determined by X-ray diffraction, electron-microscopic techniques - scanning electron microscopy (SEM) and transmission electron microscopy (TEM). According to X-ray diffraction, the value of particle size for Al2O3 nanopowders is 20.85 nm. In the following, the antibacterial activity of Al₂O₃ nanoparticles was assessed on three gram positive and three gram negative bacteria by radial diffusion assay and measurement of minimum inhibitory concentration (MIC). The toxicity of Al₂O₃ nanopowders on blood cells was also assessed. The results showed that this nanostructure has potent antibacterial activity against gram positive and gram negative bacteria. The synthesized Al₂O₃ nanopowders showed the antimicrobial activity against antibiotic resistant bacterium, Staphylococcus aureus. Significant antibacterial activity of this nanostructure was seen to have a greatest effect on Bacillus cereus with the MIC value of 9.2 μg/ml; while, among bacterial strains, Salmonella typhimurium was investigated to be the most resistant one with the MIC of 35.6 μg/ml. Al₂O₃ nanopowders showed no toxicity on blood cells. according to acquired data in this study, Al₂O₃ nanopowders may be a good material for inhibition of biofilm formation.

Abstract: Through simulation analysis of the blood cell by Abques under the function of the different pressures, the change of the cell’s axial diameter and the importance of the effect of external force and double concave shape on the erythrocyte’s deformability are obtained. It lays the foundation for the research artificial organs lubrication.

Abstract: With the development of DPM (digital phase microscopy) and FCM (flow cytometry), techniques of cell recognition are getting more and more applications in many fields. Researches on the information from cells are very important to these techniques. In this paper, focusing on the technique of analyzing light scattering information and its relation with the morphological structures of the leucocytes and erythrocytes have been done. Based on the VirtualLab simulation techniques, the light scattering images of amplitude, phase and polarization of these typical cells have been obtained. It is found that the amplitude, phase and polarization of these cells are closely related to their morphological structures by analyzing the images, which is very useful to identify biological cells.

Abstract: For studying the effect between short laser pulse and red blood cell (RBC) in a more accurate and powerful way, the light beam characters of a focused femtosecond pulse are studied with a simulation method, and then, a mixed wave-propagating model (MWP) is put forward after analyzing these characters, in which, light beam is thought as propagating in a Gaussian focused shape. In addition, a mathematical processing and linear absorption model in the focused irradiated region of RBC is built based on analyzing its physical mechanism. Finally, the temperature distribution within the RBC is gotten by data simulating calculation, which shows that the temperature variety caused by linear absorption in the focal region is rather small.

Abstract: Samples of zirconia and a bioinert SiO2-containing glass with different surface roughness were immersed into human whole blood for different settling times to investigate the adhesion and attachment of blood cells onto these materials. The cell/material interface was directly observed by scanning electron microscopy (SEM). The results indicate that the blood cells preserved their physiology and attaching capability regardless the type of material, surface roughness, and settling time. The SEM images strongly indicate the normal function of adhesion proteins.