Papers by Keyword: Dental Caries

Abstract: This study aims to create a gel base composition that has the potential to be combined with hydroxyapatite from the biogenic material Crassostrea gigas as a gel that can repair dental caries. The base gel composition consists of Na-CMC, guar gum, and glycerin which can dissolve the HA element without settling so that it can be applied well to the teeth. nano HA contained in Crassostrea gigas can potentially remineralize and improve caries in teeth. Therefore, it is inevitable that the base gel is safe to make composites with nano HA as a function of repairing dental caries. The potential of HA as a tooth remineralization material was proven by the SEM, FTIR, and XRD characterization of CaCO₃ and CaO, which have sharp crystallinity. The base gel is safe to be applied to the bones of the teeth by the MTT test treatment. This proves that the base gel is not toxic and has high viability of 92.66% at a dose of 31.25 μg/mL. The IC50 value was 688.6 μg/ml. These results are safe to be applied with nano HA material and are safe to be applied to the bones of the teeth.

Abstract: Besides the prevention strategies against early stage dental caries, restoration is a preferable way to prevent decayed tooth from further deterioration. This study aimed to compare the mechanical strengths of carious tooth, traditionally restored tooth, and novel conservatively restored teeth under occlusal loading. The two-dimensional (2D) finite element method (FEM) was applied to quantify and compare maximum tensile stresses thereby predicting the initiation of crack. Taking into consideration of peak tensile stresses, it was found that the conservative (minimal intervention) restorations exhibited better fracture resistance than traditional restoration.

Abstract: The paper is concerned with the investigation of dental caries treatment by the modern method based on the application of special composite material that can diffuse into the damaged zone, harden by light and prevent tooth decay. Carious disease was modeled as a diffusion process of acid penetration from the oral cavity into the tooth enamel with further dissolution of dental hard tissues in the subsurface layer of enamel. The model of dental caries was mathematically formulated. The solution was obtained by a numerical method using MATLAB. It is shown that the proposed model adequately describes the properties of the examined dental system.

Abstract: The purpose of the study was to identify the influence of the amount of fluoride release from glass ionomer cements on survival of bacterial strains responsible for the development of secondary caries. All developed cements had an antibacterial impact on the strains used in the study. The study demonstrated that the cements exhibit greater antibacterial activity against Streptococcus mutans than Streptococcus sanguinis. The numbers of bacteria count in cultures on the developed cements were approximately 10 times lower compared to the control culture after 24 h, 48 h, 72 h and 7 days. The developed cements had initially (1-2 days) greater antibacterial impact against the strains used in the study, which corresponds to the greatest daily amount of fluoride released from the cements. Following the initial period, the antibacterial activity of all the cements remained roughly at the same level.

Abstract: This investigation is based on the premise that heavy metals are sequestered by the mineral phase of teeth [1,2], hydroxyapatite, during their formation and there is a relation between heavy metal pollution and progressive destruction of human primary tooth. Our study was carried out on temporary molars – sound and carious - extracted from children up to 6 year old, residing in an area of Romania known to be highly polluted with heavy metals (Pb and Cd). In carious dentin extracts we found increased levels of collagen type 1 and alkaline phosphatase activity that can be correlated with the remineralization processus during teeth decay. Gelatin zymography shown increased MMP-1 (type-I collagenase) and MMP-2 (gelatinase-A) activities only in dentin extract from carious teeth isolated from children residing in a highly polluted area, suggesting their role in pathological extracellular matrix (ECM) remodeling and degradation processes in the progression of carious decay.