Papers by Keyword: Early Diagnosis

Abstract: Rare earth poisoning is becoming a more and more serious problem for the people, even worse there were no effective early diagnosis, prevention and treatments for that. In this study, the confocal micro-Raman spectroscopy was success used to monitor the variations of Raman spectra from the erythrocytes during the rare earth poisoning in mice, and the intensity heavily depended on the concentration, especially peaks at 756 cm^-1(tryptophan), 1224 cm^-1 and 1344 cm^-1(CH₂/CH₃ stretch), 1548 cm^-1(amide II) and 1566 cm^-1(amide II) which can be as the diagnostic biomarkers.

Abstract: In view of the status and shortages of clinical diagnosis of urinary stone disease, a kind of early diagnostic analyzer of urinary stones based on nanotechnology was put forward in this article. The relationship between the properties of urinary crystallites and formation of urinary stones was studied by detecting the urinary crystallites of less than 1000 nm in more than 300 cases of urinary stone formers and more than 300 cases of healthy controls. The average diameter, particle size distribution and the amount ratio of urine crystallites with different size in the two kinds of urines were significantly different. Base on these data we developed an intelligent diagnosis analyzer of urinary stones, which could help for early prediction of urolithiasis occurrence. The analyzer made no damage to human body for the reason of urine detection. The result analysis is simple, direct, fast and low-cost, and it overcomes some shortages of the existing detection technology on urolithiasis.