Papers by Keyword: Nuclear Medicine

Abstract: Nuclear medicine is a medical science that utilizes radionuclide with gamma ray radiation energy to ionizing the patient’s object either aimed for diagnostic imaging or cancer therapy. Total number of nuclear medicine facilities in Indonesia is 17 hospitals. Unfortunately, there are only 10 hospitals that actively carrying out nuclear medicine services. In order to support the Indonesia cancer management commitment program, the Ministry of Health urges the nuclear medicine facility in Indonesia need to be improved both the quality and facility’s requirement. The standard of nuclear medicine facility services in Indonesia is regulated by the Ministry of Health decree number 008/ MENKES/SK/I/2009, yet unfortunately it has not regulated any specified facility’s technical requirements including layout design, mechanical and electrical aspects. Hence, in this research, we conducted a literature review on the nuclear medicine service facilities’ requirements, referring to the Ministry of Health, the Indonesia Nuclear Energy Agency, and the International Health Facility Guidelines. We conducted thoroughly field observations in ten nuclear medicine facilities in Indonesia to propose the technical requirements and room’s layout design recommendations for nuclear medicine facility in Indonesia. In conclusion of this investigation, the availability of room, utility and instrumentation of nuclear medicine in Indonesia mostly meet the International guidelines, except the room construction aspect. Therefore, our study will promote this shortcoming to fulfill the facility’s requirement recommendation in new regulation of nuclear medicine facilities in Indonesia in the near future for the sake of better patients’ and healthworkers’ safety.

Abstract: A simple solution for fulfilling biosafety and national drug agency demands of radiation and biosafety during Ga-68 radionuclide containing radiopharmaceutical production (RP) by small scale laboratories has been demonstrated based on a novel sterile seal concept of multi-layer bag system prototype. These mid-and inner enclosures of the prototype with vial inside were sterilized by 50 kGy of gamma radiation. The microbial safety validation based on two-week testing confirmed successful sterilization of the sealing bags with vails. The analysis of physicochemical properties, namely mechanical properties, gel fraction studies revealed that sterilization did not cause any undesired changes in developed materials, compared to non-irradiated control samples.

Abstract: Results of obtaining of ¹⁸⁶Re for nuclear medicine using 13 MeV deuterons were presented. Cross section and yield of ¹⁸⁶W(d,2n)¹⁸⁶Re reaction were experimentally measured in the deuterons energy range from the threshold up to 13 MeV. The total yield of ¹⁸⁶Re in the energy range 12.5/6.43 MeV from natural tungsten was measured as (2.3 ± 0.15) MBq/(uA·h). The yield of the ¹⁸⁶Re from enriched ¹⁸⁶W for deuteron energy 12.5 MeV was evaluated as (8.2 ± 0.13)MBq/(uA·h). Possibility of ¹⁸⁶Re obtaining in sufficient quantities for a radiopharmaceuticals synthesis was established. On the basis of data on the yield ¹⁸⁶Re it is confidently expected that using of Tomsk Polytechnic University cyclotron can produce enough amount of ¹⁸⁶Re for using in nuclear medicine