Papers by Keyword: Polyethylene Glycol (PEG)

Abstract: This research demonstrates the production of membranes utilizing polyethersulfone (PES). Cellulose Acetate (CA) at 5% and Polyethylene Glycol (PEG) at 5% are incorporated into the PES membrane as additives, while ethanol serves as a variable non-solvent in the coagulation bath. The incorporation of CA and PEG additives serves to enhance the performance and characteristics of PES membranes. Fabrication of PES membranes utilizing the non-solvent induced phase separation (NIPS) technique. The impact of additive incorporation was assessed through various characterization tests, including Swelling degree, Tensile strength, contact angle, Scanning Electron Microscopy (SEM), and Fourier transform infrared (FTIR). The results indicated that the swelling degree value increased from 13.66% (PES) to 39.40% with the addition of PEG and CA. Nevertheless, the membrane's mechanical strength was diminished as a result of the inclusion of PEG. PES/CA exhibits the highest tensile strength value at 1.8 MPa, while PES/PEG has a peak of 1.4 MPa. The optimal contact angle measurement was achieved on the PES/CA/PEG membrane at 50°. The SEM characterization results indicated an increase in membrane pore size, with the modified membrane exhibiting a pore size range of 0.331-0.664 μm. The incorporation of 60% ethanol as a non-solvent resulted in the maximum swelling degree value of 41.05%. In conclusion, the characteristics of the membrane are influenced by the combination of additive Cellulose Acetate (CA) and Polyethylene Glycol (PEG) through blending.

Abstract: Chitosan (CS) is known for excellent biodegradability and low immunogenicity. However, its low water solubility has hampered CS biomedical application. In this study, we aimed to modify CS with polyethylene glycol (PEG) to improve water solubility and explored the possibility to use as a drug delivery vehicle. Degree of substitution of PEG on CS was varied, ranged from 16% to 78%. After dispersing in water, CS-PEG₇₅₀ and CS-PEG₅₀₀₀ could spontaneously form small nanoaggreagtes (NGs) at low concentration, with critical aggregation concentration ranged from 32 μg/mL to 112 μg/mL. Upon encapsulation of curcumin, all NGs were slightly bigger in size. CS-PEG₇₅₀ (1:40) NGs showed the highest entrapment efficiency at 59%, while CS-PEG₅₀₀₀ (1:40) and (1:60) NGs exhibited 36.9% and 36.5% entrapment efficiency, respectively. With few steps of modification, this modified CS copolymers reveal improved water solubility and decent entrapment efficiency. Thus this copolymer is a potential contender as a drug delivery vehicle.

Abstract: Bioactivity is an important aspect in biomaterial science ensuring materials used are safe for clinical application. The study describes fabrication of composites containing polylactic acid (PLA) – polyethylene glycol (PEG) with incorporation of sol-gel derived 45S5 bioactive glass (BG). Thermal analysis via Differential Thermal Analysis shows a favorable point over degree of crystallization that influence cells attachment, although non-significant difference in values indicates BG has homogenously dispersed. This correlates to X-ray diffraction analysis where non-significant difference is seen in intensities of the diffraction peaks, which confirms low impact of BG brittleness properties over the fabricated composite. Composites’ pH and degradation study in Simulated Body Fluid shows a steady increment profile over time and lower degradation rate for the composite after incorporation of BG. In vitro cell proliferation study also showed that HDF cells seeded on composite film of P/BG2.5 exhibit highest cell viability with steady increment of proliferation throughout the observation period.

Abstract: Bioadhesives have much potential in the medical field as an alternative to sutures in internal surgery. They are easier to use and have better long-term results. Improvement of a new class of adhesives, tannic acid-polyethylene glycol (TAPE), was done by mixing it with gelatin, since it was found that TAPE alone could not be applied to certain internal applications like in inguinal hernia. It failed to close a fresh inguinal hernia sac. Characterization tests were done on the new material, TAPE-gelatin, which proved to have a tissue adhesion strength of 0.41 MPa which is 5 times greater than fibrin glue, good blood biocompatibility with blood clotting index of 97.46%, burst pressure strength that can withstand 1000 mL that is 10 times more than the volume in the peritoneal cavity, and cheaper, with a production cost of Php28.50, than commercially available bioadhesives, which can reach up to Php2,000 – Php30,000 per application. With its desirable properties, cheaper production cost, and large potential for scalability, TAPE-gelatin as a new candidate for medical adhesive was established.

Abstract: the PEG with the molecular weights(MW) ranging from 200 to 2000 have been extensively investigated for Fenton oxidation. The affectingfactors such as pH, dosage of hydrogen peroxide and FeSO4•7H2O was studied in the experiment. The experimental results showed that the dosage of Fenton's reagent ( FeSO4•7H2O was 0.3g/L and 30%H2O2 was 0.5ml/L）was 3:5 and the pH was 3 at the room temperature, the highest CODcr removal ratio can be up to 84%.

Abstract: In this work, the effects of binder compositions on the mechanical properties, density, volume shrinkage and microstructure of sintered alumina were investigated. Three different formulations of alumina samples were prepared by mixing alumina with 3 % of poly (ethylene glycol) (PEG) with 1 to 3 wt% of poly (vinyl alcohol) (PVA) binders. The degradation temperature of binder was investigated by means of thermogravimetry analysis (TGA). Diametral compressive test was conducted to determine the tensile strength of sintered alumina. Scanning electron microscopy (SEM) was used to characterise the microstructure and fracture surface analysis. It was found that PVA binder plays important roles in sintering of alumina. The relative density and tensile strength increase as the percentages of PVA increase for each sintering temperature but the volume shrinkages are not much affected by binder composition. The results inferred that alumina samples which have 3%wtPVA-3%wtPEG binder sintered at 1600 °C shows the highest tensile strength (129 MPa) compared to other formulations.

Abstract: Metal foams are well-known as engineered materials with unique combination of physical and mechanical properties, yielding an attractive material for use in the aerospace industry, automotive and medical industry. In this study the method that been used to produce SS316L foam is slurry method. Slurry of stainless steel is prepared by mixing binder material such as methyl cellulose (CMC), polyethylene glycol (PEG) and distilled water by using ball milling machine. Then, the sample is sintered at different temperatures which are 1300°C, 1350°C and 1400°C. The value of porosity and density of SS316L foam are collected utilizing Archimedes method. As the result, the porosity percentage found in the range of 4.77 % to 59.80% meanwhile density value ranging from 0.402g/cm3 to 0.952g/cm3. The highest value of porosity is 59.80% at 1300°C for 40wt% SS316L, while, the highest value of density is 0.952g/cm³ at 1350°C for 60wt% SS316L. These results was followed the theory of porosity and density which are the value of porosity is inversely proportional to the density.

Abstract: The polyethylene glycol is a kind of phase change energy storage material with small thermal hysteresis effect, the phase change enthalpy and phase transition temperature varies with its different molecular weight. This article summarizes polyethylene glycol as research progress of phase change energy storage material, which mainly discusses the preparation methods and outlook about form-stable phase change materials.

Abstract: This study investigates the effect of Sodium Chloride (NaCl) coagulant medium with different concentration to produce Polysulfone (PSf) ultrafiltration (UF) asymmetric membrane. The polymer membrane prepared by a phase inversion method using Polysulfone (PSf) as a base polymer, Polyethylene glycol (PEG) 400MW as copolymer additive, N-methyl-2-pyrrolidone (NMP) as solvent and NaCl coagulant medium with different concentration as nonsolvent. In this work, the concentration of immersion medium for membrane phase immersion process prepared based on different coagulation concentration medium NaCl was modified repeatedly in the range of 1-5%. These membrane performance were analyzed via pure water permeation and solute rejection of humic acid. Based on these results, the membrane immersed in 4% concentration of NaCl coagulant medium showed the highest pure water permeation (235.69 l.m^-2. h^-1) and solute rejection of humic acid which is up to 98%.

Abstract: In the present work, polysulfone (PSf) ultrafiltration membranes were prepared by solution casting. The effects of rice husk silica (RHS) on the surface properties of the PSf/Polyethylene glycol (PEG) membrane were observed and investigated. Characterizations were conducted to determine the membrane cross-section area and RHS distribution. The structure of RHS and morphology of membrane were analyzed by using X-ray diffractometer (XRD) and scanning electron microscope (SEM). XRD pattern showed that the amorphous silica was produced from rice husk ash (RHA). The analysis of SEM indicates that the addition of RHS obviously changed the microstructure of the membrane especially at top layer and sub layer.