Papers by Keyword: Single Crystal Diffraction

Abstract: The main object of the present invention is to provide an improved process for the preparation of Iloperidone, which would be more simple, economical and easy to implement on large scale preparation. In this paper, 1,3-difluorobenzene and 1-(4-hydroxy-3-methoxyphenyl) ethanone are starting materials. And then tartaric acid is added. The key intermediate (Z)-4-(2,4-difluorobenzoyl) piperidine oxime is obtained through stereoselectivity. With the key intermediate and 1-(4-(3-chloropropoxy)-3-methoxyphenyl) ethanone, the target product is obtained directly under the condition of catalyst.

Abstract: The measurement of Pendellösungs oscillations was used to observe the time dependent nucleation of oxygen in a Czochralski grown single crystal at 750°C. It is shown, that the theoretical approach of the statistical dynamical theory describes the data well. Within the framework of this theory it is possible to determine the static Debye-Waller-factor as a function of the annealing time by evaluating the mean value of the Bragg intensity and the period length. The temperature influence on the Pendellösungs distance was corrected for by measurement of a Float-zone sample at the same temperature.