Papers by Keyword: Stenosis

Abstract: Atherosclerosis occurs due to plaque thickening in arteries, reducing blood flow and oxygen supply to tissues. This study models blood flow in a bifurcated stenosed artery under a uniform magnetic field, analyzing magnetohydrodynamics (MHD) hybrid blood nanofluid flow with heat transfer. Using COMSOL Multiphysics, the laminar and Newtonian flow of a hybrid blood nanofluid with silver (Ag) and gold (Au) nanoparticles is simulated. Results, validated by existing literature, highlight key parameters such as velocity, heat flux, and wall shear stress (WSS). The study shows that Ag and Au nanoparticles improve blood flow, reducing recirculation in stenosed arteries, offering the potential for nanomedicine treatments.

Abstract: The shape and mechanical properties of abnormal red blood cells (RBCs) change considerably in comparison with healthy red blood cells (RBCs). In this paper, we perform numerical investigation of the hemodynamics of RBCs in microvessels with stenosis. Our model is based on an immersed boundary-fictitious domain method. We employ a spring model for representing deformability of RBC membrane. The proposed model successfully simulates complex motion and deformation of RBCs in micro scale flow. Our method would be helpful for further understandings of pathology of malaria and some other blood disorders.

Abstract: This paper presents a fluid-cell interaction algorithm using the immersed boundary coupled fictitious domain method. We discuss the application of this method to the numerical investigation of motion and deformation of erythrocytes in two-dimensional stenotic microvessels. The erythrocytes are modeled as biconcave-shaped closed membranes filled with cytoplasm. Simulation results of multiple erythrocytes traversing the stenosis in Poiseuille flow are presented. This algorithm is applicable to a large class of problems involving fluid flow with complex geometry and fluid-cell interactions.

Abstract: Blood-viscosity reducing drugs like “Pentoxifylline” improve blood flow by making the blood less viscous. The resistance to flow of blood in diabetic patients is higher than in non-diabetic patients. Thus diabetic patients with higher resistance to flow are more prone to high blood pressure. Therefore the resistance to blood flow in case of diabetic patients may be reduced by reducing viscosity of the plasma. Viscosity of plasma can be reducing by giving Pentoxifylline. In this paper an attempt has been made to investigate the blood flow behaviour and significance of non-Newtonian viscosity through a stenosed artery using Bingham Plastic fluid model. Numerical illustrations presented at the end of the paper provide the results for the resistance to flow, apparent viscosity and the wall shear stress through their graphical representations. It has been shown that the resistance to flow, apparent viscosity and wall shear stress increases with the size of the stenosis but these increases are comparatively small due to non-Newtonian behaviour of the blood indicating the usefulness of its rheological character in the functioning of the diseased arterial circulation.

Abstract: In this present study a two-phase model for the influence of aspirin on peripheral layer viscosity for physiological characteristics of blood flow through stenosed blood vessels using Casson’s fluid model has been obtained. Flow of blood with axially non-symmetric but radially symmetric stenosis geometry is considered. The non-linear pressure equations have been solved with help of boundary conditions and the results are displayed graphically for different flow characteristics. It was found that the resistance to flow decreases as stenosis shape parameter increases whereas the resistance to flow increases with increasing values of stenosis length, stenosis size and peripheral layer viscosity. The effects of stenosis severity and wall shear stress are discussed in the present computational analysis. Comparisons between the measured and computed peripheral layer viscosity profiles are favourable to the solutions. As a result it can be concluded that a regular dose of Asprin decreases the blood viscosity by diluting the blood of diabetic patients which ultimately decreases the blood pressure. For the validation of the numerical model, the computation results are compared with the experimental data and results from published literature.