Nickel-base superalloy is a special super heat resistant alloy developed by U.S in 1970s. It is mainly applied to turbine parts as well as high-temperature components. Nickel-base superalloys exhibit an excellent high strength, low thermal conductivity and creep resistance as well as work hardening. It is the most difficult to be machined with high-speed cutting among different sorts of high-temperature superalloys and is a material presenting multifold challenges for machining. The purpose of this study aims at the machinability of Nickel-base alloys. Engineering statistical analysis was employed to observe the cutting speeds, feed rates and surface roughness at first place. The researcher further applied the half-normal probability plot (HNPP), Pareto analysis and ANOVA to identify the cross effects and probed into the characteristics of Nibase alloy.