Hybrid microspheres with a polystyrene core coated with magnetite nanoparticles were prepared by two techniques. Firstly, monodispersed functional polystyrene latex particles were prepared by emulsion polymerization. In a general way chemical groups may be introduced through polymerizable surfactant or functional monomer. Magnetite acidic or alkaline sol was added in, then magnetite nanoparticles were absorbed onto latex particles by electrostatic attraction and core-shell composite particles were formed. Secondly, core-shell composite particles were prepared by miniemulsion polymerization. To modify the tendency of conglomeration of magnetite and increase the amount of magnetic particles onto the composite particles, silane coupling agent MPS was used as surface modification agent for magnetite. A series of different size and coating morphology magnetic hybrid particles were prepared through the adjustment of some experiment parameters. The obtained functional core-shell particles were characterized by FTIR, TEM, etc.