The aim of this study is to explore alloy 718 that treated at an optimal HIP process, and then imposed various solid-solution temperatures and aging treatment. The experimental results indicated that Laves and δ precipitations obviously appeared within the grain boundary, under HIP treatment and lower solid-solution temperatures (940°C), which would result in poor mechanical properties. However, Laves and δ phase can be completely dissolved at 1020°C 1 hour solid-solution treatment. The tensile strength was increased to 1331.5 MPa, and elongation reached up to 6.1% under a 1020°C solid-solution and aging treatment. Increasing the solid-solution temperature to 1060°C would cause parts of the NbC to dissolve, thus a large number of the thin sheet-shaped NbC would appear in the solid-solution and aging specimen. The yield stress is slight increase, but a lot of NbC precipitations will result in the decreasing tensile strength (1298.8 MPa) and elongation (5.4%). As a result, the optimal solid-solution treatment parameter of alloy 718 is 1020°C for 1-hour.