In this study, Nd: CW CO2 laser were used in LSA experiment on Steel C1045 with four different systems alloyed by Sub-Micron Ceramics, namely Ti+C, TiO2+C, TiC, Ti+V+C. The high hardness alloyed coating was prepared on the surface of Steel C1045 adopting laser alloying process for the ideal reinforced effect of surface that we expect. The microstructures of the four different alloy systems were analyzed by SEM. The microhardness and the friction coefficient of these laser alloying layers were examined, then the abrasion resistance and the main wear mechanism were summarized. According to the experimental results, comprehensive properties of Ti+V+C system were the most excellent in all systems.