Enterprise sustainable development emphasizes coordination of the development of economy, environment and society. The life cycle cost based on the sustainable development controls the engineering cost as well as environmental pollution and damage. The thermal power plant burns large amount of fossil fuels and discharge pollutants which cause serious pollution. Therefore the pollution control and ecological conservation make up important parts of construction and production cost, both of which are key parts of life cycle cost. This paper uses analytic hierarchy process and fuzzy comprehensive evaluation to estimate the life cycle cost and helps the enterprise to make social or temporal comparison and potentiality exploitation and to improve its sustainable development capability.