To verify the existing sports bicycle frames design and to achieve the fast and accurate self-design of frames, a simulation model of the frames is established during three development processes. First, the modal and static tests were designed for the study of a particular sports bicycle frame. Second, the initial simulation model of the frame was developed with Pro/Engineer and ANSYS Workbench software, and the simulation model was used to conduct the modal and static analysis on the frame. Finally, based on the comparison of the analysis and test result, the parameters of the simulation model were modified. The results show that the simulation model is consistent with the test result and it can be used for the optimal design of sports bicycle frame.