This work aims preparation cheaper and high performance reticulate porous ceramic (RPC) for organism carrier. The RPC were made from clay by polymeric foam replication process. The X-ray diffraction (XRD) phase analysis indicates that the RPC mainly consist of mullite when sintered at 1350°C. The surface status of different component RPC was observed under scanning electron microscopy (SEM). The bio-film properties of different component and different pore size RPC were evaluated by the removal rates of CODCr and NH3-N. The results show that the RPC had high effectiveness for microorganisms’ adsorption, the removal rates of CODCr and NH3-N are all reach to 90%, and the bio-film effect is related to porosity, pore size and surface status of the RPC, but the porosity and pore size play more important role than the surface status of these carriers in bio-film process, the RPC carriers with more porosity and suitable pore size achieve better sewage treatment effect.