Antibacterial Properties of Rose Bengal Immobilized in Polymer Supports
Photosensitizers immobilized in polymers can serve as antibacterial surfaces or coatings and can be applied for disinfection of water or medical instruments. The antibacterial activity of the immobilized photosensitizers is based on their excitation by visible light followed by energy transfer from the photosensitizers to oxygen dissolved in an aqueous phase which produces reactive oxygen species that cause irreversible damage to bacterial cells. The photosensitizer Rose Bengal immobilized in polystyrene, polycarbonate and poly (methyl methacrylate) was shown to eradicate Gram-positive Staphylococcus aureus bacteria under moderate illumination.
A. Valkov et al., "Antibacterial Properties of Rose Bengal Immobilized in Polymer Supports", Applied Mechanics and Materials, Vols. 719-720, pp. 21-24, 2015