The Effects of Polysaccharide from Gynostemma pentaphyllum Supplementation on Exhaustive Exercise-Induced Fatigue
The present study aimed to determine the effects of polysaccharides from Gynostemma Pentaphyllum (PGP) supplementation on exhaustive exercise-induced fatigue in mice. The mice were divided into four experimental groups at random, i.e. control, low-dose PGP, medium-dose PGP, and high-dose PGP treatment groups. An oral administration of distilled water was given to the mice in the control group, and different doses of PGP (100, 200 and 400 mg/kg body weight/day) were given to the mice in the treatment groups. After 28 days, the weight-loaded swimming test was performed, along with the determination of blood biochemical parameters, liver glycogen and muscle glycogen contents. The results indicated that PGP supplementation had anti-fatigue effects, which could make mice swim for a longer time to exhaustion, with the blood lactic acid, serum urea nitrogen, serum triglycerides, and serum creatine kinase contents decreased, and the liver glycogen and muscle glycogen contents increased.
M. Han and X.S. Tai
C. J. Li and A. Li, "The Effects of Polysaccharide from Gynostemma pentaphyllum Supplementation on Exhaustive Exercise-Induced Fatigue", Applied Mechanics and Materials, Vol. 730, pp. 241-244, 2015