Fluid-Structure Interaction Simulation of an Aortic Phantom with Uncertain Young's Modulus Using the Polynomial Chaos Expansion


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To add reliability to numerical simulations, Uncertainty Quantification is considered to be a crucial tool for clinical decision making. This especially holds for risk assessment of cardiovascular surgery, for which threshold parameters computed by numerical simulations are currently being discussed. A corresponding biomechanical model includes blood flow, soft tissue deformation, as well as fluid-structure coupling. Thereby, structural material parameters have a strong impact on the dynamic behavior. In practice, however, particularly the value of the Young's modulus is rarely known in a precise way, and therefore, it reflects a natural level of uncertainty. In this work we introduce a stochastic model for representing variations in the Young's modulus and quantify its effect on the wall sheer stress and von Mises stress by means of the Polynomial Chaos method. We demonstrate the use of uncertainty quantification in this context and provide numerical results based on an aortic phantom benchmark model.



Edited by:

Peter F. Pelz and Peter Groche




J. Kratzke et al., "Fluid-Structure Interaction Simulation of an Aortic Phantom with Uncertain Young's Modulus Using the Polynomial Chaos Expansion", Applied Mechanics and Materials, Vol. 807, pp. 34-44, 2015

Online since:

November 2015




* - Corresponding Author

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