Effect of Gamma Irradiation on the Migration of Di(2-Ethylhexyl) Phthalate from Plasticized Poly(Vinyl Chloride) into Air and PVC Resin


Article Preview

The risk of di (2-ethylhexyl) phthalate (DEHP) migration from plasticized poly (vinyl chloride) (PVC) is an important issue for patients.We present a study on the effect of gamma radiation on the migration of DEHP from plasticized PVC into air and PVC as a function of time (0-28day) at 75°C.The samples were irradiated at dose of 25 kGy using a 60Co gamma radiation source.The change of weight loss at 75°C was studied as a function of time.Diffusion coefficient of samples was calculated,it was found that the diffusion coefficient significant increased after irradiation,the sample having ESO exhibited an decrease trend of DEHP migration,which shown that ESO can effectively impress the migration of DEHP from plasticized PVC either in control or irradiate samples,the same Phenomenon was found in air and PVC.The diffusion coefficient was between 8.37×10-11 and 2.68×10-10 cm2/s in air, 8.87×10-8 and 9.99×10-8 cm2/s in PVC.



Edited by:

Z.S. Liu, L.P. Xu, X.D. Liang, Z.H. Wang and H.M. Zhang




Q. Wang et al., "Effect of Gamma Irradiation on the Migration of Di(2-Ethylhexyl) Phthalate from Plasticized Poly(Vinyl Chloride) into Air and PVC Resin", Advanced Materials Research, Vol. 1015, pp. 397-400, 2014

Online since:

August 2014




* - Corresponding Author

[1] ASTM International: Complete Standard Terminology Relating to Plastics. Available at: [http: /www. astm. org/Standards/D883. htm].

[2] Ito R, Miura N, Ushiro M: Effect of gamma-ray irradiation on degradation of di(2-ethylhexyl) phthalate in polyvinyl chloride sheet. International Journal of Pharmaceutics. Vol. 376(2009), pp.213-218.

DOI: https://doi.org/10.1016/j.ijpharm.2009.04.019

[3] P.D. Zygoura A.E. Goulas K.A. Riganakos: Michael G. Kontominas. Migration of di-(2-ethylhexyl) adipate and acetyltributyl citrate plasticizers from food-grade PVC film into isooctane: Effect of gamma radiation. Journal of Food Engineering. Vol. 78(2007).

DOI: https://doi.org/10.1016/j.jfoodeng.2005.12.004

[4] A. Zoller, A. Marcilla: Soft PVC foams: Study of the gelation, fusion, and foaming processes.I. Phtha -late ester plasticizers. Journal of Applied Polymer Science. Vol. 121(2011)No. (3), p.1495–1505.

DOI: https://doi.org/10.1002/app.33671

[5] A.P. Tüzüm Demir, S. Ulutan: Migration of Phthalate and Non-Phthalate Plasticizers Out of Plasticiz -ed PVC Films into Air. Journal of applied polymer science. Vol. 128(2013)No. 3, p.1948-(1961).

DOI: https://doi.org/10.1002/app.38291

[6] Little, A. D. Final summary report: A study of indirect food additive migration. FDA contract 1983: 223-77-2360.

[7] V. PAPAKONSTANTINOU,C.D. PAPASPYRIDES. Plasticizer Migration From Plasticized Into Unplasticized Poly(Viny1 Chloride). Journal of vinyl Technology. Vol. 16(1994)No. (4), pp.192-196.

DOI: https://doi.org/10.1002/vnl.730160404

[8] Ito R., Seshimo FMiura N., Kawaguchi M. et al. Effect of sterilization process on the formation of mono (2-ethylhexyl)phthalate from di(2-ethylhexyl)phthalate. Journal of Pharmaceutical and Biomedical Analysis. Vol. 41(2006), pp.455-460.