Cytotoxicity Test of Brown Silk from Attacus atlas L. on Rat Smooth Muscle Cells
Natural brown silk biomaterial from silkworm Attacus atlas L. (A. atlas L.) is a biopolymer that has many advantages compared to commercial silk from Bombyx mori (B. mori). The aim of this study was to investigate the cytotoxicity of A. atlas L. silk on rat smooth muscle cells with the direct method of methyl thiazolyl tetrazolium assay compared to commercial surgical suture silk. The result showed that brown colored natural silk has low cytotoxicity as same as commercial surgical suture silk with slightly lower cell viability. It was found that A. atlas L. silk potentially can developed to be surgical suture thread as a new expectation of biopolymer material in biomedical products.
Ferry Iskandar, Satria Zulkarnaen Bisri, Prof. Mikrajuddin Abdullah, Prof. Khairurrijal and Prof. Kikuo Okuyama
M. F. Ulum and D. Noviana, "Cytotoxicity Test of Brown Silk from Attacus atlas L. on Rat Smooth Muscle Cells", Advanced Materials Research, Vol. 1112, pp. 433-436, 2015