Effects of Material on the Deployment of Coronary Stents

Abstract:

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Coronary stents have been more and more widely used in clinic over the past decade. There have been a large number of stents made of different biocompatible materials available commercially in the market. It is however unclear which is more suitable to specific patients. This raises a major concern whether the choice of stents could be assessed before a delivery surgery. This paper aims to provide a computational approach for evaluating the effect of stent materials on biomechanical outcomes of the deployments of stents in different patient. It will review the typical biomaterials being used for coronary stents, seeking to qualitatively assess them for use as coronary stents. Non-linear explicit finite element (FE) procedure is carried out using the Palmaz-Schatz stent geometry to quantitatively predict the effect of mechanical properties of these biomaterials on stent and coronary artery behavior during stent deployment. A quantitative comparison is made for exploring the effect of different materials on the deployment of stents. The study is considered significant in understanding the role how stent materials affect biomechanical responses to the coronary stenting. It provides a new methodology to promote a patient-specific assessment before surgery.

Info:

Periodical:

Advanced Materials Research (Volumes 123-125)

Edited by:

Joong Hee Lee

Pages:

315-318

DOI:

10.4028/www.scientific.net/AMR.123-125.315

Citation:

S. Tammareddi and Q. Li, "Effects of Material on the Deployment of Coronary Stents", Advanced Materials Research, Vols. 123-125, pp. 315-318, 2010

Online since:

August 2010

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Price:

$38.00

[1] Mani, G., M. D. Feldman, et al. (2007). Coronary Stents: A materials perspective., Biomaterials 28: 1689-1710.

DOI: 10.1016/j.biomaterials.2006.11.042

[2] Gu, L., S. Santra, et al. (2005). Finite element analysis of covered microstents., Journal of Biomechanics 38: 1221-1227.

DOI: 10.1016/j.jbiomech.2004.06.008

[3] Gervaso, F., C. Capelli, et al. (2008). On the effects of different strategies in modelling balloon-expandable stenting by means of finite element method., Journal of Biomechanics 41: 1206-1212.

DOI: 10.1016/j.jbiomech.2008.01.027

[4] Capelli, C., F. Gervaso, et al. (2009). Assessment of tissue prolapse after balloon-expandable stenting: Influence of stent cell geometry., Medical Engineering & Physics 31: 441-447.

DOI: 10.1016/j.medengphy.2008.11.002

[5] Park, J. B. and Y. K. Kim (2003). Ch. 1: Metallic Biomaterials. Biomaterials. Principals and Applications. J. B. Park and J. D. Bronzino, CRC Press: pp.1-20.

[6] Saltzman, W. M. (2009). Biomedical Engineering, Bridging Medicine and Technology, Cambridge University Press: Ch15, p.540.

[7] Prior, A. M. (1994). Applications of implicit and explicit finite element techniques to metal forming., Journal of Materials Processing Technology 45: 649-656.

DOI: 10.1016/0924-0136(94)90413-8

[8] Migliavacca, F., L. Petrini, et al. (2002). Mechanical behaviour of coronary stents investigated through the finite element method., Journal of Biomechanics 35: 803-811.

DOI: 10.1016/s0021-9290(02)00033-7

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