Synthesis of Star-Shaped PLA via Direct Melt Polycondensation: 1. Using L-LA as Starting Material
Using 1,3,5-benzenetrioxyundecanol (mTU) as the core, and L-lactic acid (L-LA) as starting material, a novel star-shaped poly(L-lactic acid) (SPLLA) was synthesized via direct melt polycondensation with simple process and low-cost. The obtained biodegradable polymer SPLLA was systematically characterized with the intrinsic viscosity [η], FTIR, 1H-NMR, GPC and XRD. The Mw, Tg, Tm, ΔH, crystallinity, crystallite size of all SPLLA basically increased with the increase of the molar feed ratio n(L-LA) : n(mTU). When n(L-LA) : n(mTU) was 500:1, the biggest Mw was 8600, but all Mw meet the requirement for drug delivery application.
Zhengyi Jiang, Jingtao Han and Xianghua Liu
Z. Y. Wang et al., "Synthesis of Star-Shaped PLA via Direct Melt Polycondensation: 1. Using L-LA as Starting Material", Advanced Materials Research, Vols. 152-153, pp. 1236-1239, 2011