The sandstone in pavement engineering is mostly obtained by mining mountain or river way, which has brought beyond-retrieve destruction for natural environment, such as mountain bareness and ecological damage. So lightweight epoxy asphalt mixture(LEAM) incorporating different replacement percentage of granulated lightweight aggregate(GLWA) and circular lightweight aggregate(CLWA) by weight were researched. Then performances of strength, rutting resistance, moisture susceptibility of epoxy asphalt mixture incorporating GLWA and CLWA and the economical efficiency were evaluated, and results presented all performances met the specification and LEAM was more economical than the mixture without GLWA or CLWA. And the shape and replacement percentage of lightweight aggregate could improve or weaken mixture performance and the change amplitude was different. The mixture incorporating 40% CLWA replacement was determined to be the most suitable mixture for steel deck pavement of long span or special construction bridge, such as moveable bridge.