The development of health functional materials and the healthy law were focused on in this paper. Several world-renowned health regimen liquid was introduced, and the basic principles of health from the material, medicine and biological sciences were analyzed, then a healthy and anti-aging effect cell-food that containing circulating balanced ions was developed, and finally the health ion methodology was proposed. Ion is the forth morphology existing in soild, liquid and gas. Ion is smaller than nano, but it has a higher potential and can be applied in electronic, energy, environment, building materials, food, textile, agriculture, health industry and so on, such as ‘Solid Ion Science’ of electronic, semiconductor, battery, ‘Ion Liquid’ of pollution-free chemistry, ionic conductivity cement, water changed to fuel, purify CO2 in industry and more. So we can conclude that ion technology will become one of the most cutting-edge technologies after nano technology. In this paper, healthy materials and circulating ions were mainly introduced.