Preparation and Characterization of Thermo-Sensitive Hydroxypropylmethyl Cellulose/Poly (N-Isopropylacrylamide) Hydrogel


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The best is to read these instructions and follow the outline of this text. Thermo-sensitive hydrogels based on linear HPMC and cross-linked PNIPAAm were prepared by the semi-IPN technique. The interior morphology of hydrogels was investigated by fluorescent microscope. The hydrogels were characterized by Fourier transform infrared (FTIR). The thermo-sensitivity, equilibrium swelling rate and swelling dynamics of these hydrogels were investigated. The chemical compositions and structures of the semi-hydrogels were similar to each other, as measured by FTIR. The results indicated that the swelling ratio of the hydrogel decreased with increasing temperature. In pH 7.4 buffer solution (37°C ), when the weight ratio of HPMC to NIPAAm was 1/100, the swelling ratio was the maximum. In comparision with a conventional PNIPA hydrogel, the semi-IPN hydrogel synthesized with hydroxypropyl-methyl cellulose exhibits a much faster response rate to temperature changes. For example, PNI-H05 loses 87% water within 5min, whereas the conventional hydrogel loses only about 25% water within 5 min. and about 50% water within 50 min.



Advanced Materials Research (Volumes 194-196)

Edited by:

Jianmin Zeng, Taosen Li, Shaojian Ma, Zhengyi Jiang and Daoguo Yang




Y. L. Xiao et al., "Preparation and Characterization of Thermo-Sensitive Hydroxypropylmethyl Cellulose/Poly (N-Isopropylacrylamide) Hydrogel", Advanced Materials Research, Vols. 194-196, pp. 773-776, 2011

Online since:

February 2011




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