Introduction on superiority of high performance concrete (HPC), then present and compare five methods of HPC mix design in detail. Both fixed grout volume method and cement coefficient method are concentrating on the research of cementing materials. Infilled coefficient method and mix design method based on the best paste-aggregate ratio obtain the optimized sand ratio in the best voidless condition. Overall calculation method is based on the volume model, elicits formula of sand ratio and water consumption and ends the method of looking up the table for sand ratio and water content. Through the comparison of methods, we find that it's a trend that HPC mix design method can develop from semi-quantitative to quantitative, from experience to science.