Based on the ZigBee technology, Home monitoring system has been designed and implemented in Wireless Sensor Network, intelligent wheelchair, and communication modules. The system works on the existing TD-SCDMA network. The working principle of the system, hardware and software designing are described in detail. After the test, the information collection of indoor environment and user physiological indexes were realized well, and could transmit in time. The purpose of remote monitoring has been achieved. This system has high practical value.