Solvent-Free N-Alkylation of Phthalimide Catalyzed by Basic Ionic Liquids
Solvent-free N-alkylation of phthalimide with alkyl halides catalyzed by basic ionic liquids was developed in this conmmunication. With a comparative study, [Bmim]OH (1-butyl-3-methyl imidazolium hydroxide) exhibited the highest catalytic activity among the selected basic ionic liquids, which afforded a convenient, efficient and general protocol for N-alkyl phthalimides exclusively.
Zhong Cao, Lixian Sun, Xueqiang Cao, Yinghe He
Z. G. Le et al., "Solvent-Free N-Alkylation of Phthalimide Catalyzed by Basic Ionic Liquids", Advanced Materials Research, Vols. 233-235, pp. 1431-1434, 2011