Analysis of Penicillin Antibiotics in Cosmetics Using Ultra Performance Liquid Chromatography
In this study, the utral-performance liquid chromatography (UPLC) method with UV-PDA was utilized to develop a rapid, sensitive reliable method for analysis of 5 penicillin antibiotics in cosmetics productions which the presence of these penicillin in commercial cosmetics samples is prohibited. The samples was prepared by liquid-liquid extraction and then the analyses was carried out on UPLC-PDA. The chromatographic column used was Acquity UPLCTM BEH C18 (100 mm ×2.1 mm,1.7μm) and the mobile phase is Acetonitrile and potassium dihydrogen phosphate(PBS) Buffer solution pH 5.5. Chromatographic separation was obtained by gradient elution.
Zhong Cao, Lixian Sun, Xueqiang Cao, Yinghe He
Z. J. Wu and Y. Peng, "Analysis of Penicillin Antibiotics in Cosmetics Using Ultra Performance Liquid Chromatography", Advanced Materials Research, Vols. 233-235, pp. 87-90, 2011