Study on Preparation, Biological Activity and Thermal Decomposition of N-Benzoyl-N'-(4-Chlorobenzamido) Thiourea

Abstract:

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A novel compound N-benzoyl-N'-(4-chlorobenzamido) thiourea was prepared from benzoyl isothiocyanate which was obtained from benzoyl chloride and potassium thiocyanate, and 4-chlorobenzoyl hydrazine which was obtained from ethyl 4-chlorobenzoate and hydrazine hydrate. IR, 1H NMR, 13C NMR and elemental analysis were utilized to determine the structure of the thiourea. The biological tests indicated that the target compound had antibacterial activity against bacillus subtilis and taphylo-coccus aurers. Meanwhile, the thermal stability was investigated by thermogrativity(TG) and differential thermogrativity (DTG). The results demonstrated there was one weight-loss in the thermal decomposition process. The thermal kinetics equation obtained describing the thermal decomposition process was expressed as .

Info:

Periodical:

Advanced Materials Research (Volumes 236-238)

Edited by:

Zhong Cao, Yinghe He, Lixian Sun and Xueqiang Cao

Pages:

1914-1918

DOI:

10.4028/www.scientific.net/AMR.236-238.1914

Citation:

R. L. Li et al., "Study on Preparation, Biological Activity and Thermal Decomposition of N-Benzoyl-N'-(4-Chlorobenzamido) Thiourea", Advanced Materials Research, Vols. 236-238, pp. 1914-1918, 2011

Online since:

May 2011

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Price:

$35.00

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