Preparation of Vitamin E Liposomes by the Thin Film Method and Study on its Leakage Rate
This text adopted the thin film method to prepare the vitamin E liposomes, the influence of proportion of components in vitamin E liposomes, and experiment condition on the envelopment rate were studied. The results showed that the optimum condition of the making technology of the vitamin E liposomes was:temperature42°C,m(vitamin E):m(lecithin)=1:25,m(vitamin E) :m(the cholesterol )=1:3, m(vitamin E) :m(the octadecylamine )=5:1, the phosphate buffer solution was 20 ml. In this case, the entrapment efficiency of the vitamin E liposomes was 76% .This method was accurate, and applicable for the preparation of vitamin E liposomes, and the property of it was very stable.
Zhong Cao, Yinghe He, Lixian Sun and Xueqiang Cao
W. G. Zhang et al., "Preparation of Vitamin E Liposomes by the Thin Film Method and Study on its Leakage Rate", Advanced Materials Research, Vols. 236-238, pp. 2207-2210, 2011