Synthesis of Novel Drug Benvitimod

Abstract:

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Benvitimod (3,5-dihydroxy-4-i-propylstilbene) is a novel drug developed for common skin disorders such as atopic dermatitis by Welichem Biotech Inc. in Canada and Celestial Pharmaceuticals (Shenzhen) Co. Ltd. in China. But the ideal synthesis method is not reported so far. Herein an efficient synthesis method which is operated under the mild conditions is reported. According this route, the total yield will reach 40.3 - 48.1% and the benefits of the improved method are easily operating and environment friendly.

Info:

Periodical:

Advanced Materials Research (Volumes 236-238)

Edited by:

Zhong Cao, Yinghe He, Lixian Sun and Xueqiang Cao

Pages:

2378-2382

DOI:

10.4028/www.scientific.net/AMR.236-238.2378

Citation:

J. G. Gao et al., "Synthesis of Novel Drug Benvitimod", Advanced Materials Research, Vols. 236-238, pp. 2378-2382, 2011

Online since:

May 2011

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Price:

$35.00

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