Chiral Separation of Amino Acid Derivatives by Molecular Imprinting Technique

Abstract:

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Molecularly imprinted polymers, based on the surface-modified silica gel, were prepared with silylanized silica gel as a carrier, acrylamide as functional monomer, ethylene dimethacrylate (EDMA) as crosslinker and Boc-L-phenylalanine as the template molecule. The results of HPLC shows that the imprinted polymers have good specific recognition of Boc-L-phenylalanine. The baseline separation of Boc-phenylalanine enantiomer was achieved in 20 min, the resolution was 1.84 and the maximum adsorption capacity was 6788 mg g-1.

Info:

Periodical:

Advanced Materials Research (Volumes 239-242)

Edited by:

Zhong Cao, Xueqiang Cao, Lixian Sun, Yinghe He

Pages:

2545-2548

DOI:

10.4028/www.scientific.net/AMR.239-242.2545

Citation:

L. Q. Su et al., "Chiral Separation of Amino Acid Derivatives by Molecular Imprinting Technique", Advanced Materials Research, Vols. 239-242, pp. 2545-2548, 2011

Online since:

May 2011

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Price:

$35.00

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