Study on the Effect of Functional Monomer on the Binding Characteristics of Molecularly Imprinted Polymer
Three kinds of molecularly imprinted polymers (MIPs) were prepared with S-naproxen as template molecule, and methacrylic acid, acrylamide, 4-vinyl pyridine as functional monomers, respectively. The interaction between template molecule and different monomers were analyzed by UV spectra. Binding experiments and Scatchard analysis were adopted to compare the binding characteristics of MIPs. The results showed that the MIP based on 4-vinyl pyridine possessed the highest adsorption amount of 1.73 μmol for the template molecule, while the MIP based on methacrylic acid presented the lowest binding characteristic, which correlated positively with the interaction strength concluded by UV analysis.
Zhong Cao, Xueqiang Cao, Lixian Sun, Yinghe He
F. Rong et al., "Study on the Effect of Functional Monomer on the Binding Characteristics of Molecularly Imprinted Polymer", Advanced Materials Research, Vols. 239-242, pp. 821-824, 2011