The Efficient Synthesis of 1,3-Diallyloxy-2-Propanol without Solvent
An efficient and practical protocol for the preparation of 1,3-diallyloxy-2-propanol has been developed by one-pot reaction between epichlorohydrin and allyl alcohol in the presence of KOH without solvent at room temperature. This preliminary approach provides an environmentally-friendly synthetic route to 1,3-diallyloxy-2-propanol with many advantages, i. e., low cost, high yield, easy purification, mild reaction conditions, and large scale production.
X. M. Liu et al., "The Efficient Synthesis of 1,3-Diallyloxy-2-Propanol without Solvent", Advanced Materials Research, Vols. 311-313, pp. 2106-2109, 2011