Repair of Rabbit Facial Nerve with Amniotic Extracellular Matrix Based on Biological Material
Objective: To evaluate the effects of amniotic extracellular matrix (AECM) on the repairation of facial nerve in rabbits. Methods: The transected nerve ends of the facial nerves of rabbits were then repaired with the AECM nerve conduit or an autologous nerve graft. After 3 months, the animals’ neural conductive velocity were determined. The myelinated fibers across the specimen were counted with histological examination. Results: The total count of medullated nerve fibers varied significantly, but the nerve conduction velocity had no significance between the AECM grafts and the autologous nerve grafts. Conclusion: AECM could become the biocompatible material for repairing the peripheral nerves.
Helen Zhang and David Jin
Z. Gao et al., "Repair of Rabbit Facial Nerve with Amniotic Extracellular Matrix Based on Biological Material", Advanced Materials Research, Vol. 322, pp. 169-172, 2011