Preparation and Characterization of Biocompatible Magnetic Fluids


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Nano-Fe3O4 magnetic particles were prepared by ultrasonic emulsion method and then were dispersed into water with chitosan or folate as surfactants for biocompatible water-based Fe3O4 magnetic fluid. The cubic inverse spinel structure of Fe3O4 nanoparticles were analyzed by X-ray diffraction technique (XRD). The saturation magnetizations of different magnetic particles were tested by a vibrating sample magnetometer (VSM). The morphologies of nanoparticles were observed by transmission electron microscope (TEM). The particle size was about uniform 10-20 nm, and their shape was approximately spherical. Meanwhile, dispersity was improved markedly after the surface modification. Comparing to magnetic fluid with chitosan modification, magnetic fluid was coated with chitosan and folate gets higher dispersity and stability when both of them have same saturation magnetizations.



Edited by:

Xiaodong Zhang, Zhijiu Ai, Prasad Yarlagadda and Yun-Hae Kim




Y. Ji et al., "Preparation and Characterization of Biocompatible Magnetic Fluids", Advanced Materials Research, Vol. 338, pp. 384-387, 2011

Online since:

September 2011




[1] Y. B. Zhao, Z. M. Qiu and J. Y. Huang: Chin. J. Chem. Eng. Vol. 16 (2008), p.451.

[2] C. X. Lu, J. M. Du and G. F. Shi: J. Clin. Rehabil. Tissue. Eng. Res. Vol. 12(2008), p.1089.

[3] D. C. Li, R. Chun, Y. Chen and R. C. Hao: Phys. Pro. Vol. 9 (2010), p.248.

[4] C. Shen, W. Huang, G. L. Ma and X. L. Wang: Surf. Coat. Technol. Vol. 204 (2009), p.433.

[5] T. L. Guo and H. B. Li: Met. Mine. Vol. 394 (2009), p.35.

[6] S. Chen, C.L. Chiang and S. Hsieh: J. Magn. Magn. Mater. Vol. 322 (2010), p.247.

[7] G. Q. Wang, H. Li, R. L. Hu, X. F. He, D. S. Wei and W. Meng: Chin. J. Lung Cancer. Vol. 3 (2011), p.181.

[8] A. S. Lübbe, C. Alexiou and C. Bergemann: J. Surg. Res. Vol. 95 (2001), p.200.

[9] D. Cao, J. Yin, H. Cao and S. Y. Yuan: Mater. Rev. Vol. 11 (2008), p.51.

[10] S. H. Kim, J. H. Jeong, C. O. Joe and T. G. Park: J. Controlled Release. Vol. 103 (2005), p.625.

[11] Y. Q. Zheng, C. Y. Tong, B. Wang, Y. Xie, H. D. Liao, D. Li and X. M. Liu: Chin. Sci. Bull. Vol. 54 (2009), p. (2065).

[12] Y. Ji, H. P. Shao, Z. M. Guo, T. Lin and D. H. Yang: J. Uni. Sci. Technol. Beijing. Vol. 33 (2011), p.751.