Effects of Nutritional Factors on Production of Bacterial Bioactive Metabolites against Aflatoxin Biosynthesis

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Bacillus subtilis is potential to play an important role on biological control of aflatoxin-producing fungi. The liquid fermentation medium of Bacillus subtilis LN for production of bioactive metabolites inhibitory to mycelial growth and aflatoxin biosynthesis was optimized by single factor experiments. The results showed that optimum carbon source was glucose, the optimum nitrogen source was soy peptone, and the optimum inorganic salt was MgSO4. These screened optimal carbon, nitrogen and inorganic salt sources could be used for high yield fermentation of bioactive metabolites for developing biopesticide against aflatoxin contamination in foods.

Info:

Periodical:

Advanced Materials Research (Volumes 343-344)

Edited by:

David Wang

Pages:

564-567

DOI:

10.4028/www.scientific.net/AMR.343-344.564

Citation:

Z. Wang et al., "Effects of Nutritional Factors on Production of Bacterial Bioactive Metabolites against Aflatoxin Biosynthesis", Advanced Materials Research, Vols. 343-344, pp. 564-567, 2012

Online since:

September 2011

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Price:

$38.00

[1] K. Abbas. Aflatoxin and food safety, 1st ed, CRC Taylor and Francis, (2005).

[2] Park DL. . 68–73. Surveillance programmes for managing risks from naturally occurring roxicants, in Food Addit Contam, 1995, May-Jun, 12(3), pp.361-371.

[3] Pei-Sheng Yan, Yuan Song, et al. Cyclo(L-Leucyl-L-Prolyl) Produced by Achromobacter xylosoxidans Inhibits Aflatoxin Production by Aspergillus parasiticus. Applied and Environmental Microbiology, 2004, 70(12), pp.7466-7473.

DOI: 10.1128/aem.70.12.7466-7473.2004

[4] Kimura N, Hirano S. Inhibitory strains of Bacillus subtilis for growth and aflatoxin-production of aflatoxienic fungi, Agricultural and Biological Chemistry, 1988, 52, pp.1173-1179.

DOI: 10.1271/bbb1961.52.1173

[5] Smith J S, Dorner J W, Cole R J. Testing Bacillus subtilis as a possible aflatoxin inhibitor in stored farmers stock peanuts, Proc Am Peanut Res Educ Soc, 1990, 22, p.35.

[6] Moyne A. L., R. Shelby, T. E. Cleveland and S. Tuzun. Bacillomycin D: an Iturin with Antifungal Activity against Aspergillus Flavus, J Appl Microbiol, 2001, Apr, 90(4), pp.622-629.

DOI: 10.1046/j.1365-2672.2001.01290.x

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