The purpose of the research was to establish an index analysis system for evaluating the low-carbon cities development. DPSIR model was adopted to build an index system for low-carbon city evaluation. In this research, two different approaches were adopted for the empirical analysis of low-carbon city development evaluation. The one approach was DPSIR model for building an index system of low-carbon city evaluation; the other was the Factor Analysis which was introduced to calculate the weight of factors and evaluate low-carbon development in Yangtze River Delta. The results disclosed that the technology factor took account more weight in “driving force” index, the resource consumption factor play more important role in “pressure” index; the weight of exhaust emission factor was equal to the social low-carbon level factor in “state” index. The conclusion of empirical research was that the cities such as Yancheng, Wuxi, and Suzhou had higher scores, but the low-carbon city development in Zhejiang province was better than the cities in Jiangsu province and Shanghai area.